Uji aktivitas antibakteri dari ekstrak metanol, fraksi heksan, fraksi etil asetat dan fraksi air daun kari (murraya koenigii (l.) Spreng)

  • Desi Sagita Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi
  • Taufik Khoirudin Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi
  • Netty Netty Fakultas Farmasi Universitas Andalas, Padang

Abstract

Antibacterial activity of extracts and fractions of curry leaves against Staphylococcus aureus and Escherichia coli has been done. Methanol was used for the extraction of the curry leaves, extract methanol was fractionated using different solvent polarity ie n-hexane, ethyl acetate and water. Antibacterial activity of extracts and fractions were measured by the appearance zones of inhibition by diffusion methode. The result show, hexane fraction was more effective against S. aureus than extract methanol and ethyl acetate fraction. The antibacterial activity of methanol extract, hexane fraction and ethyl acetate fraction at concentration (100 ppm) showed maximum zone of inhibition (5.2, 6.6 and 5.3 mm, respectively) againt S. aureus. At concentration (250 ppm) showed maximum zone of inhibition (7.3, 8.8 and 6 mm, respectively). At concentration (500 ppm) showed maximum zone of inhibition (9, 10.8 and 7.3 mm, respectively). At concentration (1000 ppm) showed maximum zone of inhibition (11, 13.8 and 8.6 mm, respectively). Methanol extract, hexane, ethyl acetate and water fraction didnot showed zones of inhibition on E.coli.

Published
2021-01-07
How to Cite
SAGITA, Desi; KHOIRUDIN, Taufik; NETTY, Netty. Uji aktivitas antibakteri dari ekstrak metanol, fraksi heksan, fraksi etil asetat dan fraksi air daun kari (murraya koenigii (l.) Spreng). Tropharm (Trobosan Pharmacy), [S.l.], v. 1, n. 1, p. 24-31, jan. 2021. Available at: <https://jurnal.stikes-hi.ac.id/index.php/tropharm/article/view/470>. Date accessed: 28 may 2024.