Pembuatan ekstrak kering daun sirsak (Annona muricata L.) dan uji aktivitas antioksidan

Abstract

Antioxidant are substances that can resist the influence of the dangers of free radicals for med as a result of oxidative metabolism, which is the result of chemical reactions and metabolic processes that occurin the body. This research was conducted to determine the effect of making dry extract of Annona muriculata L. leaves on antioxidant activity. This research used simplicia of Annona muriculata L. leaves with extraction using 96% ethanol, 70% ethanol and methanol. The results showed that the viscous extract from the Annona muriculata L. leaves each solventh as a higher antioxidant activity than the dry extract from the Annona muriculata L. leaves each solvent, IC50 value of viscous extract ethanol 96%, 70% and methanol obtained respectively 58.02, 85.80 and74.78 µg / mL. while IC50 value of dry extract 96% ethanol, 70% and methanol obtained respectively 495,75, 194,04 and 241,58 µg/mL, by using acomparisonVitaminCobtainedIC50 of49.26µg / mL. Manufacture of dry extract of leaves of Annona muricata L. with added lactosa can incease the antioxidant activity its.